August 2005- In this study, Cowan, Atienza, Melton, and Eggan reprogram somatic cells to an embryonic state by fusing human embryonic stem (hES) cells with human fibroblasts. Their “morphology, growth rate, and antigen expression patterns” were “characteristic of hES cells” (Cowan et al., 2005). This experiment showed that “human embryonic stem cells are able to reprogram the nuclei of fully differentiated human somatic cells, apparently conferring on them a pluripotent state” (Surani 2005).
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