Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

July 2008- This study examined a patient with ALS disease. In the study, human iPS cells were generated from an 82-year-old woman with ALS disease, which were then “direct differentiated into those neural cells destroyed by ALS,” demonstrating promise for patient-specific cell therapy and showing that iPS cells can be produced from elderly individuals stricken afflicted with a chronic disease (Dimos et al, 2008).